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PDRN is derived from salmon DNA and is rich in nucleic acids — the building blocks of DNA. In cosmetic use it is valued for its conditioning and revitalizing properties, helping to support the appearance of firmer, smoother, more resilient-looking skin.
As skin ages, its visible firmness and elasticity naturally decline, leading to the appearance of fine lines and wrinkles. PDRN-based formulations help support the look of firmness and elasticity while improving the appearance of fine lines. The formula is also rich in antioxidant ingredients that help defend against the visible effects of environmental oxidative stress.
Alongside its anti-aging appeal, the formula has strong moisturizing properties, making it well suited to dry or dehydrated-looking skin. It helps support the skin's natural moisture barrier, reducing the look of dryness and keeping skin feeling hydrated and supple.
Elysee Exosome PDRN is formulated for use within professional treatment protocols and is compatible with professional microneedling systems. As an alternative approach for professionals, the salmon DNA ampoule is valued for barrier repair, hydration, brightening, the appearance of dark spots, and calming stressed-looking skin. It is also used in scalp-focused professional protocols.
Compatible home-care and portable options for approved clients include the 24K Gold Needle and the Medi Nanopen Pro.
| Product Name | Dermafirm Elysee Exosome PDRN — Professional Bundle |
| Net Weight | 4 ml x 12 vials |
| Format | Medical-grade ampoule serum (skin booster) |
| Key Actives | PDRN, Sodium DNA, 8 Peptides, Centella Asiatica Leaf Vesicles |
| Recommended User | Licensed skincare and medical professionals |
| Application Method | Professional topical protocols, including use with professional microneedling systems |
| Treatment Areas | Face, professionally selected targeted areas, and scalp protocols |
Elysee Exosome PDRN is available exclusively to verified skincare and medical professionals — physicians, nurses, medspas, spas, and licensed estheticians. Approved accounts see the Add to Bag button, exclusive professional pricing, and full treatment protocols.
Approval is fast, and registration takes less than two minutes.
Not a professional? Ask your esthetician or provider about a PDRN skin booster treatment at your next visit.
A straightforward protocol designed to integrate PDRN into your existing professional treatment workflow.
Cleanse the skin thoroughly, removing all makeup, sunscreen, excess oil, and surface impurities.
Exfoliate according to your professional protocol and the client's skin condition, then prepare the treatment area.
Apply an appropriate amount of Elysee Exosome PDRN evenly across the treatment area.
Work the serum into the skin using a Nanopen or professional microneedling system, adjusting settings and technique to the client's skin condition, sensitivity, and treatment goals.
Follow with a compatible calming or barrier-support product, and finish with broad-spectrum sunscreen for daytime treatments.
For professional use only. All treatment methods must fall within the treating provider's license and scope of practice, and follow all applicable state and local regulations.
Do not use on clients with active skin infections, open lesions, active cold sores, severe inflammation, sunburn, or a known sensitivity to any ingredient. Exercise additional caution with highly reactive, sensitized, or barrier-impaired skin, and with clients who have a fish or seafood-derived ingredient sensitivity.
A professional consultation and patch test are recommended before the first treatment. Treatment intensity, frequency, and product quantity should be determined by a properly trained and licensed professional.
Discontinue use and seek appropriate medical advice if severe or persistent irritation occurs.
Register your practice for professional access and pricing.
Elysee Exosome PDRN combines salmon DNA-derived polydeoxyribonucleotides with an 8-peptide complex, hydrolyzed collagen, brightening actives, and Centella Asiatica leaf vesicles.
Derived from salmon DNA and rich in nucleic acids — the building blocks of DNA. Valued in professional skincare for conditioning and revitalizing the skin, supporting the appearance of barrier recovery, firmness, and a healthy, resilient-looking complexion.
Works alongside PDRN to condition the skin and support the appearance of a healthy, well-hydrated surface.
Acetyl Octapeptide-3, Acetyl Hexapeptide-8, Dipeptide-2, Tripeptide-1, Pentapeptide-13, Acetyl Tetrapeptide-5, and Copper Tripeptide-1 support the appearance of firmness, elasticity, and smoother texture.
Known for soothing and conditioning properties — comforts stressed-looking skin and supports the appearance of a healthy skin barrier.
A highly effective humectant that draws moisture into the skin's surface, helping maintain hydration and a plump, supple look.
Supports a brighter, more even-looking tone and helps improve the appearance of dark spots and uneven texture.
Antioxidant ingredients that help defend against the visible effects of environmental oxidative stress and support a luminous complexion.
Conditions the skin surface and supports a smooth, supple, well-moisturized feel.
Purchasing requires a verified professional account. Registration takes under two minutes.
PDRN stands for Polydeoxyribonucleotide, a salmon DNA-derived ingredient rich in nucleic acids. In professional skincare it is valued for conditioning and revitalizing the skin, supporting the look of barrier recovery, hydration, brightness, and firmness.
Each bundle contains twelve 4 ml ampoules of Elysee Exosome PDRN — enough to build a repeatable treatment series or service multiple clients at an efficient per-treatment cost.
It is compatible with professional microneedling systems such as the Bella Professional MTS and the CODE-X Microneedling Pen, as well as portable options including the Medi Nanopen Pro and the 24K Gold Needle. All treatment methods must fall within your license and scope of practice.
It is used in protocols targeting barrier repair, dryness and dehydration, dullness and dark spots, the appearance of fine lines and loss of firmness, and stressed or irritated-looking skin. It is also used in scalp-focused professional protocols.
A professional consultation and patch test are recommended before the first treatment. Use caution with highly reactive, sensitized, or barrier-impaired skin, and avoid use on active infections, open lesions, cold sores, severe inflammation, or sunburn. Note that PDRN is salmon-derived, so screen clients for fish or seafood-derived ingredient sensitivity.
Treatment frequency should be determined by the treating professional based on the client's skin condition, sensitivity, and treatment history. Many professionals build a series using the 12-vial bundle, allowing the skin to return to baseline between sessions.
This is a professional-only product available to verified skincare and medical professionals — physicians, nurses, medspas, spas, and licensed estheticians. Register for a professional account here; once approved, the Add to Bag button and professional pricing become visible.
Contact jessica@dermafirmusa.com for a detailed microneedling protocol and professional support materials.
Approved professionals receive complete treatment documentation and support.