


Advanced H+L Hyaluronic Acid + Polynucleotide Skin Remodeling System
PURIHILO PN is an advanced professional aesthetic formulation combining high- and low-molecular-weight hyaluronic acid (H+L HA) with polynucleotide (PN) in a concentrated skin-remodeling platform.
Developed for professional aesthetic protocols, PURIHILO PN provides a multidimensional approach to skin revitalization by supporting hydration, elasticity, structural integrity, collagen synthesis and tissue remodeling.
PURIHILO PN utilizes ABEP Hybrid Technology, a patented technology designed to synthesize and stabilize high- and low-molecular-weight hyaluronic acid through acid-base equilibrium.
According to the manufacturer's professional guide, this process prevents hyaluronic acid denaturation by avoiding thermal synthesis and uses no BDDE or other chemical cross-linking agents.
PURIHILO PN combines high- and low-molecular-weight hyaluronic acid to create a stabilized hybrid complex designed for professional skin-remodeling protocols.
The high-molecular-weight HA component contributes to intensive hydration and structural support while helping maintain the extracellular matrix environment.
The low-molecular-weight HA component works as part of the stabilized H+L hybrid complex to complement the formulation's hydration and skin-remodeling profile.
Each 2.5 mL pre-filled syringe contains 25 mg of sodium polynucleotide.
PURIHILO PN is a medical-grade polynucleotide that has undergone DNA analysis.
The PN component is designed to support rejuvenating and revitalizing activity and pathways associated with collagen and elastin synthesis.
The manufacturer's professional guide identifies PURIHILO PN for tissue remodeling and improvement in skin laxity across multiple treatment areas.
PURIHILO PN combines the hydration and structural-support properties of stabilized H+L hyaluronic acid with the revitalizing characteristics of polynucleotide technology.
This dual-component approach makes PURIHILO PN particularly suited for professional aesthetic protocols focused on hydration, skin quality, elasticity, tissue remodeling and visible rejuvenation.
Net Weight: 1 x 2.5ml
*For Professionals only*
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PURIHILO PN may be incorporated into professional aesthetic treatment protocols using the BAP technique described in the manufacturer's professional guide.
The BAP technique targets anatomically selected injection points to maximize product diffusion while minimizing risk by avoiding major blood vessels and nerves.
The technique is designed to use fewer injection points while supporting effective product distribution throughout the targeted treatment area.
Identify the five BAP injection sites on each side of the face.
Inject 0.25 mL per bolus at the superficial subcutaneous layer.
Locate the treatment point at least 2 cm lateral to the outer canthus.
Draw a joining line between the nose wing and the tragus. Draw a perpendicular line starting from the pupil midline. Identify the injection point at the intersection of the two lines.
Locate the treatment point approximately 1 cm anterior to the lower border of the tragus.
Draw the midline of the chin.
Draw a horizontal line at the upper one-third of the midline from the chin tip.
From the point of intersection, move approximately 1.5 cm toward the oral commissure.
Locate the treatment point approximately 1 cm above the mandibular angle.
Identify the 10 BAP injection sites on the neck.
Pinch the skin at the injection point.
Inject 0.25 mL per bolus transversely across the skin at the superficial subcutaneous layer.
Identify the 10 BAP injection sites on the hand.
Inject 0.1 cc per point at approximately 1.5 cm intervals from the middle of the middle finger.
The manufacturer's professional guide recommends a 3 mm needle depth for the hand protocol.
The manufacturer's professional guide presents PURIHILO PN as a three-step session protocol designed to progressively enhance the effects of the HA-PN complex.
PURIHILO PN is supplied in a 2.5 mL pre-filled syringe containing a concentrated combination of high- and low-molecular-weight hyaluronic acid and sodium polynucleotide.
| High-Molecular-Weight Hyaluronic Acid | 40 mg |
|---|---|
| Low-Molecular-Weight Hyaluronic Acid | 40 mg |
| Sodium Polynucleotide | 25 mg |
| Phosphate Buffered Saline | q.s. |
The formulation contains equal quantities of high- and low-molecular-weight hyaluronic acid, providing a total of 80 mg HA in each 2.5 mL syringe.
Each 2.5 mL syringe contains 25 mg sodium polynucleotide